Do not drink coffee after taking cold medicine
Last updated 2026-09-29 — After taking cold medicine, you should not drink coffee, nor should you take it, otherwise you will have a stomachache and may even be fatal. Cold medicine has a stimulating effect on gastric mucosa, caffeine will aggravate irritation, so it will cause stomachache; cold medicine generally contains phenylpropanolamine, when taken with high amounts of caffeine products, it can increase the blood concentration by three times, leading to a sharp rise in blood pressure.
After taking cold medicine, it is not advisable to drink coffee again, and do not use coffee to take it, otherwise stomachache will occur, and may even be fatal. Cold medicines irritate the stomach mucosa, and caffeine exacerbates the irritation, resulting in stomachache. Phenylpropanolamine is commonly found in cold medicines. When taken together with high caffeine products, it can triple the blood concentration, causing a sharp rise in blood pressure, which can be fatal in severe cases.
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