Coffee may make it difficult for women to conceive.

Drinking coffee regularly may increase a woman's risk of infertility, researchers at the University of Nevada School of Medicine report in the new issue of the medical journal Pharmacology. Caffeine reduces the ability of fallopian tube cells to move, thus affecting the fertilized eggs into the uterine cavity.

Under normal circumstances, after the egg and sperm combine, they migrate from the fallopian tube to the uterine cavity, where they "settle down" and slowly develop into a fetus. A special cell on the wall of the fallopian tube plays an important role in facilitating migration.

In mice, the researchers found that caffeine reduced the activity of these cells, making it difficult for the fallopian tubes to deliver fertilized eggs to the uterine cavity.

Physiology professor Sean Ward, who participated in the study, said the new findings may explain why women who drink a lot of coffee are more difficult to conceive, which may help some women who have difficulty conceiving and allow doctors to take measures more effectively.